Description

Severe Acute Respiratory Syndrome Coronavirus-2 (SARS CoV-2), which has caused the Covid-19 pandemic has created panic in everyone’s mind, it is therefore necessary to predict protection against SARS-CoV-2, and understand the quantity, quality, and duration of the antibody response during different stages of Covid-19 and in the convalescent period.

SARS CoV-2 Neutralizing Antibody test

Quantitative FDA approved Test to detect circulating neutralizing Antibodies against SARS CoV that neutralize RBD-ACE interaction. In this regard, assessing the level of neutralizing antibodies (NAbs) that block viral entry into cells could be a critical parameter in determining protection from SARS-CoV-2 and management of convalescent plasma therapies.

Who should be tested for SARS CoV- 2 Neutralizing Antibody test?

Patients with high spike Antibody titre

post vaccinated to check neutralizing Antibodies.

Frequent Travelers- high neutralizing Ab confirms better immunity to fight SARS CoV-2

Deciding plasma therapy

Specimen Type: Serum/Plasma

Advantages of SARS CoV-2 Neutralizing Antibody test

Individual Comprehensive Antibody panels for detection of Spike Antibody & Neutralizing Antibody

Quantitative results

Better sensitivity & specificity

Faster reporting in current scenario

Interpretive reporting for determining seroconversion, plasma therapy & accessing vaccine candidates

References-

a) SARS-CoV-2 specific antibody and neutralization assays reveal the wide range of the humoral immune response to virus | Communications Biology (nature.com)

b) Hoffmann, M. et al. SARS-CoV-2 cell entry depends on ACE2 and TMPRSS2 and is blocked by a clinically proven protease inhibitor. Cell 181, 271–280.e278 (2020).