Also known 3-Hydroxy-3-Methylglutaryl-CoA reductase
(HMGCR)
Details
Description
HMGCR autoantibodies supports the clinical
diagnosis of necrotizing autoimmune myopathy (NAM). Confirmation with muscle
biopsy is recommended. Negative results do not exclude the diagnosis of
necrotizing autoimmune myopathy (NAM). approximately 35% of cases of NAM are
associated with autoantibodies against 3-hydroxy-3-methylglutaryl-CoA reductase
(HMGCR).